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Regain Your Natural Beauty


Hyaluronidase is an enzyme that can be injected to dissolve dermal filler and is the best treatment option for those looking at dissolving lip filler and reducing any lumps or puffiness associated with dermal filler in the face or body.

Hyaluronidase is a medicine that should only be administered by a doctor skilled in its use, only in a clinical environment, and only after a consultation and a test patch as there is a risk of serious allergic reaction.


  • You will have a consultation with one of our doctors. 

  • The consultation will determine if Hyaluronidase treatment is suitable for you. If you wish to proceed with the treatment, a patch test will be scheduled. This can be on the same day or the following day, whichever suits.

  • Numbing cream will be applied to the target area. Prior to injection, the Hyaluronidase dose is diluted with saline using the appropriate titration.

Hyaluronidase dissolves some hyaluronic acid dermal filler immediately and continues to work for up to 7 days.

Procedure Time

45 minutes

Duration Of Actions


Course or one-off treatment

Two appointments (patch test required)

Onset Of Results

Immediate improvement and full result in 10 days

Risks & Complications

Swelling, Redness, Bruising



Anti WrinkleAnti Wrinkle Treatment Treatments


Can I have Dermal Filler again after Hyaluronidase? Yes, but you should wait 14 days after your treatment as the hyaluronidase can break down the new dermal filler. If you wish to do this, we can offer you the dermal re-fill treatment at a discounted price. This is something the majority of clients choose to do.

How soon can I dissolve my Dermal Filler? If you have had dermal filler it is recommended not to dissolve it for cosmetic reasons for 14 days after the initial treatment, as you are unlikely you will have seen the final result due to swelling. Where vascular compromise arises after dermal filler treatment, Hyaluronidase can be administered immediately, and should not be delayed.

Can Hyaluronidase dissolve all types of Dermal Filler? Hyaluronidase can dissolve hyaluronic acid dermal fillers e.g. Juvéderm, Restylane, Perfecta, Princess, Teosyl. However it cannot dissolve non-hyaluronic-acid dermal fillers or other filling agents e.g. Radiasse, Sculptra, Ellanse.

What are the side effects of Hyaluronidase? The most significant side-effect of hyaluronidase is an allergic reaction, which can vary in severity. Other side effects include: • Discomfort at time of injection • Swelling • Bruising • Infection • Triggering cold sores if used to dissolve filler around the mouth area • Dissolving naturally occurring hyaluronic acid • Uneven appearance following treatment • Multiple treatments may be required depending on the amount, type and location of dermal filler to be dissolved.

What is Hyaluronidase not Suitable for? Hyaluronidase is not suitable if you have a history of serious allergy e.g. anaphylaxis response to an allergen or you are allergic to bee or insect stings. For your peace of mind, we will ask to test your response to Hyaluronidase on a small area. This will immediately reveal if you have a reaction that would make Hyaluronidase unsuitable for you.

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