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Revitalize your skin with Profhilo at Aesthetic Ace Clinic for deep hydration and improved elasticity.
The BioRegenerative Signature Skin Rejuvenation

Plant stem cells + polynucleotides + sythetic exosomes + biomimetic peptides

EXOSOMES, POLYNUCLEOTIDES & STEM CELL 3-IN-1 REGENERATIVE TREATMENT

A next-generation skin rejuvenation treatment delivering visible improvements from the very first session.

This ultra-intensive, medical-grade protocol combines polynucleotides (PDRN), synthetic exosomes, and plant stem cells to activate cellular repair, enhance skin regeneration, and restore overall skin vitality.

The treatment works at a cellular level to support tissue healing, stimulate collagen production, and improve skin texture, tone, and elasticity. By harnessing advanced bio-regenerative technologies, this powerful combination targets the underlying causes of skin ageing, delivering progressive, natural-looking rejuvenation.

Ideal for patients seeking advanced skin renewal, improved firmness, hydration, and long-term skin quality enhancement.

KEY COMPONENTS AND THEIR FUNCTIONS

Polydeoxyribonucleotide (PDRN)

Function:
PDRN is a DNA-derived bioactive compound widely used in regenerative medicine for its powerful skin-repair properties. It stimulates fibroblast activity, supporting tissue regeneration and collagen production, which helps improve skin elasticity and strength.

Benefits:

  •  Enhances skin repair and renewal

  •  Reduces fine lines and wrinkles

  •  Improves skin texture and elasticity

  •  Supports overall skin health and rejuvenation

Synthetic Exosomes

Function:
Synthetic exosomes are advanced nano-messengers that enhance cellular communication within the skin. They act as delivery systems for growth factors, peptides, and regenerative signals, helping to optimise skin repair and renewal at a cellular level.

Benefits:

  •  Improves skin hydration and resilience

  •  Reduces inflammation and redness

  •  Accelerates healing and regeneration

  •  Targets photoageing and early signs of ageing

Plant Stem Cells

Function:
Plant-derived stem cells are rich in antioxidants and bioactive compounds that help protect the skin from environmental stressors while supporting its natural regenerative processes.

Benefits:

  •  Protects against oxidative and environmental damage

  •  Improves skin elasticity and firmness

  •  Reduces the appearance of wrinkles

  •  Promotes a brighter, more youthful complexion

WHAT TO EXPECT FROM THE TREATMENT

​​​

Cellular Skin Rejuvenation
The synergistic combination of PDRN, synthetic exosomes, and vegetable stem cells works at a cellular level to stimulate regeneration, improving overall skin quality, strength, and vitality.

Advanced Anti-Ageing Benefits
This treatment helps soften the appearance of fine lines and wrinkles, improves skin firmness, and supports collagen production, addressing visible signs of ageing and skin laxity.

Skin Repair & Renewal
The bio-regenerative serum supports tissue repair and healing, helping to restore damaged or compromised skin while refining texture and evening skin tone.

Improved Hydration & Radiance
Deep hydration and skin brightening lead to a smoother, more radiant complexion with a healthy, youthful glow.

APPLICATION AND TREATMENT PROTOCOL 

​​​​

Professional In-Clinic Treatment
This is a medical-grade, professional treatment performed in clinic using an advanced microneedling device. The bio-regenerative serum is delivered precisely into the skin to maximise absorption and effectiveness, ensuring safe and controlled application.

Treatment Frequency
For optimal results, a minimum of 3 sessions is recommended, spaced every 4 weeks. This allows progressive skin regeneration and collagen stimulation.

Maintenance Treatments
To maintain results and ongoing skin health, maintenance sessions can be performed every 3–4 months, depending on individual skin needs.

Combination Treatments
This treatment can be safely combined with our RF Skin Tightening device to further enhance skin firmness and rejuvenation results.

Procedure Time

30-60 minutes

Results Duration

 6-12 months

FULL RECOVERY

Immediate

Risks & Complications

Swelling, Redness, Bruising

No. of sessions

3 sessions 4 weeks apart

Anaesthetic

Local Anesthetic

Anti WrinkleAnti Wrinkle Treatment Treatments

FAQs

Is the treatment painful? The treatment is generally well tolerated. A topical numbing cream can be applied to ensure comfort during microneedling.

Is there any downtime? Downtime is minimal. Mild redness, sensitivity, or warmth may occur and usually settles within 24–48 hours.

When will I see results? Many patients notice improved hydration and glow shortly after treatment. Skin texture and firmness continue to improve over the following weeks.

How many sessions will I need? For best results, a course of 3–4 sessions spaced 4 weeks apart is recommended.

Is this treatment suitable for all skin types? Yes, it is suitable for most skin types following a full consultation to confirm suitability.

Can it be combined with other treatments? Yes, this treatment can be combined with RF Microneedling to enhance skin firmness and rejuvenation.

How long do the results last? Results can be maintained with follow-up treatments every 3–4 months, alongside appropriate skincare.

How is this treatment different from standard exosome treatments? Unlike standalone exosome treatments, this protocol combines synthetic exosomes with polynucleotides (PDRN) and plant stem cells, creating a multi-layered regenerative approach that supports both cellular signalling and tissue repair for more comprehensive skin rejuvenation.

Restore youthful glow with Profhilo at Aesthetic Ace Clinic, enhancing skin texture and tone.

How does it compare to polynucleotide-only treatments? Polynucleotide treatments mainly focus on skin repair and hydration. This advanced combination enhances those effects by also improving cellular communication, collagen stimulation, and overall skin quality.

TREATMENTS 

Dermal Fillers
Anti-Wrinkle Injections

8 Point Face Lift

Non Surgical Rhinoplasty

Brazilian Butt Lift
Fat Dissolving Injections

Skin Boosters

Platelet Rich Plasma

Microneedling

IV Vitamin Therapy
Packages

Vampire Facial
Microneedling

Mesotherapy

Hair Loss Treatment

Profhilo Skin Rejuvenation

Chemical Peel

1510 Stratford Rd, Birmingham B28 9ET

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*Disclaimer: Please be aware that results and treatment experiences may vary from patient to patient taking into consideration factors such as age, lifestyle and medical history.

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